Clinical Scenarios

Evidence-based strategies for handling real-world clinical scenarios
Each scenario, drawn from real world clinical experiences of Power to Decide’s Senior Director of Health Care and our network of expert clinicians, tackles questions you may face in the exam room.

Have a scenario you’d like us to cover? Scroll to the bottom of the page to submit your own. New scenarios are published every month. 

Latest Edition

Clinical scenario: Vasovagal reaction during an IUD insertion

Clinical scenario: Residual products of conception after medication abortion

A 26-year-old (she/her) presents to your health center four weeks after a medication abortion at eight weeks of gestation. She reports bleeding was initially heavy with blood clots, and is now lighter, but she continues to have intermittent light bleeding and mild cramping. She reports she believes she is not pregnant anymore, as pregnancy symptoms have resolved, but is not sure if things are "done."  A transvaginal ultrasound shows a heterogeneous collection and thickened endometrial stripe, without a persistent gestational sac or evidence of an ongoing pregnancy.

Clinical scenario: GLP-1 meds and oral contraceptives

A 24-year-old patient (she/her) comes in after missing a period. She has a history of PCOS and irregular periods, but reports her periods have been fairly regular over the past several months. In the clinic, her urine pregnancy test is positive. She is surprised and upset, as she’s been using a combined oral contraceptive (COC) for the past 2 years. On further history, you learn she started a weekly GLP-1 injectable for weight loss about 6 months ago that she gets from a local med spa. She doesn’t remember the exact name but thinks it starts with a “s.” Since starting the injection, she’s had intermittent nausea and a few episodes of vomiting, especially in the days after injections and after she increases the dose. She asks “how did this happen?”

Clinical Scenario: Birth control breaks

A 19-year-old patient (she/they) comes in for STI testing since they recently started seeing someone new. After reviewing their sexual history and ordering appropriate testing, the provider checks in about how their birth control pills are working for them–the chart indicates they’ve been on a combined oral contraceptive for about a year. They reply, “Oh. I stopped taking them a couple of months ago–I heard it's good to take a break once in a while.”   They don’t report side effects and share that the decision was driven by things they kept seeing online. They are not interested in having kids anytime soon.

Clinical Scenario: Complex contraception and pharmacists

An 18-year-old (she/her) started a combined hormonal contraceptive pill (COC) three months ago, prescribed by her primary care provider. She’s been taking a pill with 0.15 mg levonorgestrel/30 mcg EE. She’s now following up with you because she’s been feeling moodier since starting the pill. She’s not totally sure if the pill is to blame, but says it’s affecting her quality of life and she’s interested in talking about other options.

Research roundup: October 2025 edition

DMPA on TikTok, OTC pill sales, Misoprostol & IUD placements, Telehealth abortion & TGD populations, Abortion restrictions & infant mortality

Clinical Scenario: Dual contraceptive methods

25 y.o G0 patient (she/her) comes into the clinic for an emergency department (ED) follow up. She has a history of endometriosis and has been using a LNG 52mg IUD for contraception and management of heavy menstrual bleeding. She has no other medical conditions and does not take other medications. She went to the ED for new onset shortness of breath and was diagnosed with a spontaneous pneumothorax (collapsed lung), which was ultimately discovered to be a catamenial pneumothorax.

Clinical scenario: Hormonal birth control side effects

An 18-year-old (she/her) started a combined hormonal contraceptive pill (COC) three months ago, prescribed by her primary care provider. She’s been taking a pill with 0.15 mg levonorgestrel/30 mcg EE. She’s now following up with you because she’s been feeling moodier since starting the pill. She’s not totally sure if the pill is to blame, but says it’s affecting her quality of life and she’s interested in talking about other options.
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