Clinical Scenarios

Evidence-based strategies for handling real-world clinical scenarios
Each scenario, drawn from real world clinical experiences of Power to Decide’s Senior Director of Health Care and our network of expert clinicians, tackles questions you may face in the exam room.

Have a scenario you’d like us to cover? Scroll to the bottom of the page to submit your own. New scenarios are published every month. 

Latest Edition

Clinical scenario: GLP-1 meds and oral contraceptives

Clinical Scenario: Birth control breaks

A 19-year-old patient (she/they) comes in for STI testing since they recently started seeing someone new. After reviewing their sexual history and ordering appropriate testing, the provider checks in about how their birth control pills are working for them–the chart indicates they’ve been on a combined oral contraceptive for about a year. They reply, “Oh. I stopped taking them a couple of months ago–I heard it's good to take a break once in a while.”   They don’t report side effects and share that the decision was driven by things they kept seeing online. They are not interested in having kids anytime soon.

Clinical Scenario: Complex contraception and pharmacists

An 18-year-old (she/her) started a combined hormonal contraceptive pill (COC) three months ago, prescribed by her primary care provider. She’s been taking a pill with 0.15 mg levonorgestrel/30 mcg EE. She’s now following up with you because she’s been feeling moodier since starting the pill. She’s not totally sure if the pill is to blame, but says it’s affecting her quality of life and she’s interested in talking about other options.

Research roundup: October 2025 edition

DMPA on TikTok, OTC pill sales, Misoprostol & IUD placements, Telehealth abortion & TGD populations, Abortion restrictions & infant mortality

Clinical Scenario: Dual contraceptive methods

25 y.o G0 patient (she/her) comes into the clinic for an emergency department (ED) follow up. She has a history of endometriosis and has been using a LNG 52mg IUD for contraception and management of heavy menstrual bleeding. She has no other medical conditions and does not take other medications. She went to the ED for new onset shortness of breath and was diagnosed with a spontaneous pneumothorax (collapsed lung), which was ultimately discovered to be a catamenial pneumothorax.

Clinical scenario: Hormonal birth control side effects

An 18-year-old (she/her) started a combined hormonal contraceptive pill (COC) three months ago, prescribed by her primary care provider. She’s been taking a pill with 0.15 mg levonorgestrel/30 mcg EE. She’s now following up with you because she’s been feeling moodier since starting the pill. She’s not totally sure if the pill is to blame, but says it’s affecting her quality of life and she’s interested in talking about other options.

Clinical scenario: Pregnancy of unknown location & abortion care

A 21 year-old individual (they/them) presents requesting a medication abortion. Their LMP was five weeks ago. They had a positive home pregnancy test three days ago, confirmed in clinic. Transvaginal ultrasound shows no visible intrauterine pregnancy (no gestational sac or yolk sac) and no signs of ectopic pregnancy. They deny pelvic pain, bleeding, or spotting since their LMP.

Clinical scenario: Contraception and autoimmune conditions

A 24 year-old patient (she/her) comes into clinic. During the visit, she expresses interest in starting on a hormonal implant. She was diagnosed with systemic lupus erythematosus (SLE) six months ago and is currently taking hydroxychloroquine. The patient reports no history of low platelets, but she doesn’t know her antibody status at the time of the visit. She reports no other medical conditions or current medications.
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